VITAL-Related Publications (as of August 2021)

2021

Albert CM, Cook NR, Pester J, Moorthy MV, Ridge C, Danik JS, Gencer B, Siddiqi HK, Ng C, Gibson H, Mora S, Buring JE, Manson JE. Effect of marine omega-3 fatty acid and vitamin D supplementation on incident atrial fibrillation: a randomized clinical trial. JAMA 2021 Mar 16; 325(11):1061-1073. PMC7967086

Barbarawi M, Lakshman H, Barbarawi O, Alabdouh A, Al Kasasbeh M, Djousse L, Manson JE. Omega-3 supplementation and heart failure: A meta-analysis of 12 trials including 81,364 participants. Contemp Clin Trials 2021 May 28:106458. [e-pub ahead of print]

Bassuk SS, Chandler PD, Buring JE, Manson JE; VITAL Research Group. The VITamin D and OmegA-3 TriaL (VITAL): Do results differ by sex or race/ethnicity? Am J Lifestyle Med 2021 Jul-Aug; 15(4):372-391. PMC8299924 [e-pub 2020 Dec 24]

Chou SH, Murata EM, Yu C, Danik J, Kotler G, Cook NR, Bubes V, Mora S, Chandler PD, Tobias DK, Copeland T, Buring JE, Manson JE, LeBoff MS. Effects of vitamin D3 supplementation on body composition in the VITamin D and OmegA-3 TriaL (VITAL). J Clin Endocrinol Metab 2021 Apr 23; 106(5):1377-1388. [e-pub 2021 Jan 28] PMC8063236

Donlon CM, Chou SH, Yu CY, LeBoff MS. Accounting for surgical confounding factors affecting dual-energy x-ray absorptiometry in a large clinical trial. J Clin Densitometry [e-pub 2021 Jun 17]

Farukhi ZM, Mora S, Manson JE. Marine omega-3 fatty acids and cardiovascular disease prevention: seeking clearer water. Mayo Clin Proc 2021 Feb; 96(2):277-279.

Limonte CP, Zelnick LR, Ruzinski J, Hoofnagle AN, Thadhani R, Melamed ML, Lee IM, Buring JE, Sesso HD, Manson JE, de Boer IH. Effects of long-term vitamin D and n-3 fatty acid supplementation on inflammatory and cardiac biomarkers in patients with type 2 diabetes: secondary analyses from a randomised controlled trial. Diabetologia 2021 Feb; 64(2):437-447. [e-pub 2020 Oct 24]

MacFarlane LA, Lee IM, Katz JN, Manson JE, Costenbader KH. Reply to 'The importance of establishing a suitable study population in osteoarthritis studies'. Arthritis Rheumatol 2021 May; 73(5):901-902. [e-pub 2021 Jan 16]

Rist PM, Buring JE, Cook NR, Manson JE, Kurth T. Effect of vitamin D and/or marine n-3 fatty acid supplementation on changes in migraine frequency and severity: a randomized placebo-controlled trial. Am J Med 2021 Jun; 134(6):756-762.e5. [e-pub 2021 Jan 11] PMC8164960

Rist PM, Buring JE, Cook NR, Manson JE, Rexrode KM. Effect of vitamin D and/or omega-3 fatty acid supplementation on stroke outcomes: a randomized trial. Eur J Neurol 2021 Mar; 28(3):809-815. [e-pub 2020 Oct 31] PMC7952033

Song M, Lee IM, Manson JE, Buring JE, Dushkes R, Gordon D, Walter J, Wu K, Chan AT, Ogino S, Fuchs CS, Meyerhardt JA, Giovannucci EL. No association between vitamin D supplementation and risk of colorectal adenomas or serrated polyps in a randomized trial. Clin Gastroenterol Hepatol 2021 Jan; 19(1):128-135.e6. [e-pub 2020 Feb 13] PMC7423703

Vyas CM, Ogata S, Reynolds CF, Mischoulon D, Chang G, Cook NR, Manson JE, Crous-Bou M, De Vivo I, Okereke OI. Telomere length and its relationships with lifestyle and behavioural factors: variations by sex and race/ethnicity. Age Ageing 2021 May 5; 50(3):838-846. [e-pub 2020 Oct 1] PMC8098796


2020

Barbarawi M, Barbarawi O, Manson JE. Beneficial effects of sunlight may account for the correlation between serum vitamin D levels and cardiovascular health—Reply. JAMA Cardiol 2020; 5(1):109-110. [e-pub 2019 Nov 13]

Barbarawi M, Zayed Y, Barbarawi O, Bala A, Alabdouh A, Gakhal I, Rizk F, Alkasasbeh M, Bachuwa G, Manson JE. Effect of vitamin D supplementation on the incidence of diabetes mellitus. J Clin Endocrinol Metab 2020 Aug 1; 105(8):dgaa335. [e-pub 2020 Jun 3]

Chandler PD, Chen WY, Ajala ON, Hazra A, Cook N, Bubes V, Lee IM, Giovannucci EL, Willett W, Buring JE, Manson JE; VITAL Research Group. Effect of vitamin D3 supplements on development of advanced cancer: a secondary analysis of the VITAL randomized clinical trial. JAMA Netw Open 2020 Nov 2; 3(11):e2025850. PMC7675103

Chou SH, LeBoff MS, Manson JE. Is the sun setting on vitamin D? Clin Chem 2020 May 1; 66(5):635-637. [e-pub 2020 Apr 8] PMC7192521

Christen WG, Cook NR, Manson JE, Buring JE, Chasman DI, Lee IM, Bubes V, Li C, Haubourg M, Schaumberg DA, for the VITAL Research Group. Effect of vitamin D and ω-3 fatty acid supplementation on risk of age-related macular degeneration: an ancillary study of the VITAL randomized clinical trial. JAMA Ophthalmol 2020 Dec 1; 138(12):1280-1289. [e-pub 2020 Oct 29] PMC7596682

de Boer IH, Zelnick LR, Manson JE. Kidney function in patients with type 2 diabetes after vitamin D supplementation—Reply. JAMA 2020 Apr 14; 323(14):1411-1412.

Demler OV, Liu Y, Luttmann-Gibson H, Watrous JD, Lagerborg KA, Dashti H, Giulianini F, Heath M, Camargo CA Jr, Harris WS, Wohlgemuth JG, Andres AM, Tivari S, Long T, Najhawan M, Dao K, Prentice JG, Larsen JA, Okereke OI, Costenbader KH, Buring JE, Manson JE, Cheng S, Jain M, Mora S. One-year effects of omega-3 treatment on fatty acids, oxylipins, and related bioactive lipids and their associations with clinical lipid and inflammatory biomarkers: findings from a substudy of the Vitamin D and Omega-3 Trial (VITAL). Metabolites 2020 Oct 27; 10(11):E431. PMC7693376

Djoussé L, Cook NR, Kim E, Bodar V, Walter J, Bubes V, Luttmann-Gibson H, Mora S, Joseph J, Lee IM, Albert CM, Buring JE, Gaziano JM, Manson JE; VITAL Research Group. Supplementation with vitamin D and/or omega-3 fatty acids and incidence of heart failure hospitalization: VITAL-Heart Failure. Circulation 2020 Mar 3; 141:784-786. [e-pub 2019 Nov 11] PMC7054158

Donneyong M, Reynolds C, Mischoulon D,Chang C, Luttmann-Gibson H, Bubes V, Guilds M, Manson J, Okereke O. Protocol for studying racial/ethnic disparities in depression care using joint information from participant surveys and administrative claims databases: an observational cohort study. BMJ Open 2020; 10(1):e033173. PMC6955513

Farukhi ZM, Demler OV, Caulfield MP, Kulkarni K, Wohlgemuth J, Cobble M, Luttmann-Gibson H, Li C, Nelson JR, Cook NR, Buring JE, Krauss RM, Manson JE, Mora S. Comparison of nonfasting and fasting lipoprotein subfractions and size in 15,397 apparently healthy individuals: an analysis from the VITamin D and OmegA-3 TriaL. J Clin Lipidol 2020 Mar-Apr; 14(2):241-251. [e-pub 2020 Feb 21] PMC7166180

LeBoff MS, Chou SH, Murata EM, Donlon CM, Cook NR, Mora S, Lee IM, Kotler G, Bubes V, Buring JE, Manson JE. Effects of supplemental vitamin D on bone health outcomes in women and men in the VITamin D and OmegA-3 Fatty Acid TriaL (VITAL). Journal of Bone and Mineral Research 2020 May; 35(5):883-893. [e-pub 2020 Jan 10] PMC7217747

LeBoff MS, Murata EM, Cook NR, Cawthon P, Chou SH, Kotler G, Bubes V, Buring JE, Manson JE. VITamin D and OmegA-3 TriaL (VITAL): Effects of vitamin D supplements on risk of falls in the US population. J Clin Endocrinol Metab 2020 Sep 1; 105(9):2929-2938. [e-pub 2020 Jun 3] PMC7365686

MacFarlane LA, Cook NR, Kim E, Lee IM, Iversen MD, Gordon D, Buring JE, Katz JN, Manson JE, Costenbader KH. The effects of vitamin D and marine omega-3 fatty acid supplementation on chronic knee pain in older U.S. adults: results from a randomized trial. Arthritis Rheumatol 2020 Nov; 72(11):1836-1844. PMC7874905 [e-pub 2020 Jun 25]

Manson JE, Bassuk SS, Buring JE; VITAL Research Group. Principal results of the VITamin D and OmegA-3 TriaL (VITAL) and updated meta-analyses of relevant vitamin D trials. J Steroid Biochem Mol Biol 2020 Apr; 198:105522. [e-pub 2019 Nov 13] PMC7089819

Manson JE, Bassuk SS, Cook NR, Lee IM, Mora S, Albert CM, Buring JE; VITAL Research Group. Vitamin D, marine n-3 fatty acids, and primary prevention of cardiovascular disease: current evidence. Circ Res 2020 Jan 3; 126(1):112-128. PMC7001886

Okereke OI, Reynolds CF 3rd, Mischoulon D, Chang G, Vyas CM, Cook NR, Weinberg A, Bubes V, Copeland T, Friedenberg G, Lee IM, Buring JE, Manson JE. Effect of long-term vitamin D3 supplementation vs placebo on risk of depression or clinically relevant depressive symptoms and on change in mood scores: a randomized clinical trial. JAMA 2020 Aug 4; 324(5):471-480. PMC7403921

Rist PM, Sesso HD, Manson JE. Innovation in the design of large-scale hybrid randomized clinical trials. Contemp Clin Trials 2020 Dec; 99:106178. [e-pub 2020 Oct 18] PMC7568770

Sluyter JD, Manson JE, Scragg R. Vitamin D and clinical cancer outcomes: a review of meta-analyses. JBMR Plus 2020 Nov 4;5(1):e10420. PMC7839823

Vyas CM, Donneyong M, Mischoulon D, Chang G, Gibson H, Cook NR, Manson JE, Reynolds CF, Okereke OI. Association of race and ethnicity with late-life depression severity, symptom burden, and care. JAMA Netw Open 2020 Mar 26; 3(3):e201606. PMC7325738

Vyas CM, Ogata S, Reynolds CF 3rd, Mischoulon D, Chang G, Cook NR, Manson JE, Crous-Bou M, De Vivo I, Okereke OI. Lifestyle and behavioral factors and mitochondrial DNA copy number in a diverse cohort of mid-life and older adults. PLoS One 2020 Aug 12; 15(8):e0237235. PMC7423118


2019

Barbarawi M, Kheiri B, Zayed Y, Barbarawi O, Dhillon H, Swaid B, Yelangi A, Sundus S, Bachuwa G, Alkotob ML, Manson JE. Vitamin D supplementation and cardiovascular disease risks in more than 83 000 individuals in 21 randomized clinical trials: a meta-analysis. JAMA Cardiol 2019 Aug; 4(8):765-775. PMC6584896

Costenbader KH, MacFarlane LA, Lee I-M, Buring JE, Mora S, Bubes V, Kotler G, Camargo CA, Manson JE, Cook NR. Effects of one year of vitamin D and marine omega-3 fatty acid supplementation on biomarkers of systemic inflammation in older US adults. Clin Chem 2019 Dec; 65(12):1508-1521. [e-pub 2019 Nov 7] PMC6883134

de Boer IH, Zelnick LR, Ruzinski J, Friedenberg G, Duszlak J, Bubes VY, Hoofnagle AN, Thadhani R, Glynn RJ, Buring JE, Sesso HD, Manson JE. Effect of vitamin D and omega-3 fatty acid supplementation on kidney function in patients with type 2 diabetes: a randomized clinical trial. JAMA 2019 Nov 19; 322(19):1899-1909. [e-pub 2019 Nov 8] PMC6865245

Hiemstra T, Lim K, Thadhani R, Manson JE. Vitamin D and atherosclerotic cardiovascular disease. J Clin Endocrinol Metab 2019 Sep; 104(9):4033-4050. PMC7112191

Hu Y, Hu FB, Manson JE. Marine omega-3 supplementation and cardiovascular disease: an updated meta-analysis of 13 randomized controlled trials involving 127,477 participants. J Am Heart Assoc 2019 Oct; 8(19):e013543. [e-pub 2019 Sep 30] PMC6806028

Keum N, Lee DH, Greenwood DC, Manson JE, Giovannucci E. Vitamin D supplements and total cancer incidence and mortality: a meta-analysis of randomized controlled trials. Ann Oncol 2019 May 1; 30(5):733-743. PMC6821324

Luttmann-Gibson H, Mora S, Camargo CA, Cook NR, Demler OV, Ghoshal A, Wohlgemuth J, Kulkarni K, Larsen J, Prentice J, Cobble M, Bubes V, Li C, Friedenberg G, Lee IM, Buring JE, Manson JE. Serum 25-hydroxyvitamin D in the VITamin D and OmegA-3 TriaL (VITAL): Clinical and demographic characteristics associated with baseline and change with randomized vitamin D treatment. Contemp Clin Trials 2019 Dec; 87:105854. [e-pub 2019 Oct 24] PMC6875603

Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, Gibson H, Albert CM, Gordon D, Copeland T, D'Agostino D, Friedenberg G, Ridge C, Bubes V, Giovannucci EL, Willett WC, Buring JE; VITAL Research Group. Marine n-3 fatty acids and prevention of cardiovascular disease and cancer. N Engl J Med 2019; 380(1):23-32. PMC6392053

Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, Gibson H, Gordon D, Copeland T, D'Agostino D, Friedenberg G, Ridge C, Bubes V, Giovannucci EL, Willett WC, Buring JE; VITAL Research Group. Vitamin D supplements and prevention of cancer and cardiovascular disease. N Engl J Med 2019; 380(1):33-44. PMC6425757

Manson JE, Mora S, Cook NR. Marine n-3 fatty acids and vitamin D supplementation and primary prevention. Reply. N Engl J Med. 2019 May 9; 380(19):1879-1880.

Orkaby AR, Djousse L, Manson JE. Vitamin D supplements and prevention of cardiovascular disease. Curr Opin Cardiol 2019 Nov; 34(6):700-705. [e-pub 2019 Aug 16] PMC7112175

Rist PM, Buring JE, Rexrode KM, Cook NR, Rost NS. Prospectively collected lifestyle and health information as risk factors for white matter hyperintensity volume in stroke patients. Eur J Epidemiology 2019; 34:957-965. PMC6842429

Song M, Lee IM, Manson JE, Buring JE, Dushkes R, Gordon D, Walter J, Wu K, Chan AT, Ogino S, Fuchs CS, Meyerhardt JA, Giovannucci EL; VITAL Research Group. Effect of supplementation with marine ω-3 fatty acid on risk of colorectal adenomas and serrated polyps in the US general population: a prespecified ancillary study of a randomized clinical trial. JAMA Oncol 2019 Nov 21; 6(1):108-115. PMC6902220

Vyas CM, Hazra A, Chang SC, Qiu W, Reynolds CF 3rd, Mischoulon D, Chang G, Manson JE, De Vivo I, Okereke OI. Pilot study of DNA methylation, molecular aging markers and measures of health and well-being in aging. Transl Psychiatry 2019; 9(1):118. PMC6423054

Zhang X, Tu W, Manson JE, Tinker L, Liu S, Cauley JA, Qi L, Mouton C, Martin LW, Hou L, Song Y. Racial/ethnic differences in 25-hydroxy vitamin D and parathyroid hormone levels and cardiovascular disease risk among postmenopausal women. J Am Heart Assoc 2019 Feb 19; 8(4):e011021. PMC6405652


2018

Bassuk SS, Manson JE. Randomized clinical trials of vitamin D, with a focus on the VITamin D and OmegA-3 TriaL (VITAL). In: Feldman D, Pike JW, Bouillon R, Giovannucci E, Goltzman D, Hewison M (eds.), Vitamin D, Volume 2: Health, Disease, and Therapeutics, Fourth Edition. San Diego, CA: Academic Press 2018, pp. 167-176.

Bischoff-Ferrari HA, Bhasin S, Manson JE. Preventing fractures and falls: a limited role for calcium and vitamin D supplements? JAMA 2018; 319(15):1552-1553.

Chandler PD, Tobias DK, Wang L, Smith-Warner SA, Chasman DI, Rose L, Giovannucci EL, Buring JE, Ridker PM, Cook NR, Manson JE, Sesso HD. Association between vitamin D genetic risk score and cancer risk in a large cohort of U.S. women. Nutrients 2018; 10(1). pii: E55. PMC5793283

de Boer IH, Zelnick LR, Lin J, Schaumberg D, Wang L, Ruzinski J, Friedenberg G, Duszlak J, Bubes VY, Hoofnagle AN, Thadhani R, Glynn RJ, Buring JE, Sesso HD, Manson JE. VITamin D and OmegA-3 TriaL to prevent and treat diabetic kidney disease: rationale, design, and baseline characteristics. Contemp Clin Trials 2018; 74:11-17. PMC6203639

Donlon CM, LeBoff MS, Chou SH, Cook NR, Copeland T, Buring JE, Bubes V, Kotler G, Manson JE. Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL): effects on bone structure and architecture. Contemp Clin Trials 2018; 67:56-67. PMC5877816

Goldman AL, Donlon CM, Cook NR, Manson JE, Buring JE, Copeland T, Yu CY, LeBoff MS. VITamin D and OmegA-3 TriaL (VITAL) bone health ancillary study: clinical factors associated with trabecular bone score in women and men. Osteoporos Int 2018; 29(11):2505-2515. PMC6193819

Manson JE, Bassuk SS. Vitamin and mineral supplements: what clinicians need to know. JAMA 2018; 319(9):859-860.

MacFarlane LA, Kim E, Cook NR, Lee IM, Iversen MD, Katz JN, Costenbader KH. Racial variation in total knee replacement in a diverse nationwide clinical trial. J Clin Rheumatol 2018; 24(1):1-5. PMC5741516

Okereke OI, Reynolds CF 3rd, Mischoulon D, Chang G, Cook NR, Copeland T, Friedenberg G, Buring JE, Manson JE. The VITamin D and OmegA-3 TriaL-Depression Endpoint Prevention (VITAL-DEP): Rationale and design of a large-scale ancillary study evaluating vitamin D and marine omega-3 fatty acid supplements for prevention of late-life depression. Contemp Clin Trials 2018; 68:133-145. PMC5899680

Rautiainen S, Sesso HD, Manson JE. Large-scale randomized clinical trials of bioactives and nutrients in relation to human health and disease prevention—lessons from the VITAL and COSMOS trials. Mol Aspects Med 2018; 61:12-17. PMC6004238

2017

Manson JE, Bassuk SS, Buring JE. Vitamin D, calcium, and cancer: approaching daylight? JAMA 2017; 317(12):1217-1218.

Ogino S, Jhun I, Mata DA, Soong TR, Hamada T, Liu L, Nishihara R, Giannakis M, Cao Y, Manson JE, Nowak JA, Chan AT. Integration of pharmacology, molecular pathology, and population data science to support precision gastrointestinal oncology. NPJ Precis Oncol 2017;1. pii: 40. PMC5856171

Qi L, Ma W, Heianza Y, Zheng Y, Wang T, Sun D, Rimm EB, Hu FB, Giovannucci E, Albert CM, Rexrode KM, Manson JE. Independent and synergistic associations of biomarkers of vitamin D status with risk of coronary heart disease. Arterioscler Thromb Vasc Biol 2017; 37(11):2204-2212. PMC5658253

Rhee JJ, Kim E, Buring JE, Kurth T. Fish consumption, omega-3 fatty acids, and risk of cardiovascular disease. Am J Prev Med 2017; 52(1):10-19. PMC5167636

2016

Bassuk SS, Manson JE, Lee I-M, Cook NR, Christen WG, Bubes VY, Gordon DS, Copeland T, Friedenberg G, D’Agostino DM, Ridge CY, MacFadyen JG, Kalan K, Buring JE. Baseline characteristics of participants in the Vitamin D and Omega-3 Trial (VITAL). Contemp Clinical Trials 2016; 47:235-243. PMC4818165

Dou R, Ng K, Giovannucci EL, Manson JE, Qian ZR, Ogino S. Vitamin D and colorectal cancer: epidemiological and clinical evidence. Br J Nutr 2016; 115(9):1643-1660. PMC4890569

Gold DR, Litonjua AA, Carey VJ, Manson JE, Buring JE, Lee IM, Gordon D, Walter J, Friedenberg G, Hankinson JL, Copeland T, Luttmann-Gibson H. Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults. Contemp Clin Trials 2016; 47:185-195. PMC4818187

Manson JE, Brannon PM, Rosen, CJ, Taylor CL. Vitamin D deficiency – Is there really a pandemic? N Engl J Med 2016; 375(19):1817-1820.

Pradhan AD, Manson JE. Update on the VITamin D and OmegA-3 trial (VITAL). J Steroid Biochem Mol Biol 2016; 155(Pt B):252-6. PMC4600007

Quraishi SA, Camargo CA Jr., Manson JE. Low vitamin D status in Europe: moving from evidence to sound public health policies. Am J Clin Nutr 2016; 103(4):957958. PMC4807710

Rautiainen S, Manson JE, Lichtenstein AH, Sesso HD. Dietary supplements and disease prevention—a global overview. Nat Rev Endocrinol 2016; 12(7):407-20.

Yuan C, Qian ZR, Babic A, Morales-Oyarvide V, Rubinson DA, Kraft P, Ng K, Bao Y, Giovannucci EL, Ogino S, Stampfer MJ, Gaziano JM, Sesso HD, Buring JE, Cochrane BB, Chlebowski RT, Snetselaar LG, Manson JE, Fuchs CS, Wolpin BM. Prediagnostic plasma 25-hydroxyvitamin D and pancreatic cancer survival. J Clin Oncol 2016; 34(24):2899-2905. PMC5012662

2015

Chandler PD, Buring JE, Manson JE, Giovannucci EL, Moorthy MV, Zhang S, Lee IM, Lin JH. Circulating vitamin D Levels and risk of colorectal cancer in women. Cancer Prev Res (Phila). 2015; 8(8):675-82. PMC4526335

Chandler PD, Wang L, Zhang X, Sesso HD, Moorthy MV, Obi O, Lewis J, Prince RL, Danik JS, Manson JE, LeBoff MS, Song Y. Effect of vitamin D supplementation alone or with calcium on adiposity measures: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev 2015; 73(9):577-93. PMC4537389

LeBoff MS, Yue AY, Copeland T, Cook NR, Buring JE, Manson JE. VITAL-Bone Health: rationale and design of two ancillary studies evaluating the effects of vitamin D and/or omega-3 fatty acid supplements on incident fractures and bone health outcomes in the VITamin D and OmegA-3 TriaL (VITAL). Contemp Clin Trials 2015; 41:259-68. PMC4380672

Manson JE, Bassuk SS. Determining the value of vitamin D supplementation—reply. JAMA 2015; 314(6):627-8.

Manson JE, Bassuk SS. Vitamin D research and clinical practice: at a crossroads. JAMA 2015; 313(13):1311-2

2014

Camargo CA Jr, Manson JE. Vitamin D supplementation and risk of infectious disease: no easy answers. Am J Clin Nutr 2014; 99(1):3-4. PMC3862458

Chandler PD, Scott JB, Drake BF, Ng K, Manson JE, Rifai N, Chan AT, Bennett GG, Hollis BW, Giovannucci EL, Emmons KM, Fuchs CS. Impact of vitamin D supplementation on inflammatory markers in African Americans: results of a four-arm, randomized, placebo-controlled trial. Cancer Prev Res (Phila) 2014; 7(2):218-25. PMC4038929

Kunadian V, Ford GA, Bawamia B, Qiu W, Manson JE. Vitamin D deficiency and coronary artery disease: a review of the evidence. Am Heart J 2014; 167(3):283-91.

Melamed ML, Manson JE. Genetics: vitamin D and blood pressure—a preliminary verdict. Nat Rev Endocrinol 2014; 10(10):579-80.

Schnatz PF, Manson JE. Vitamin D and cardiovascular disease: an appraisal of the evidence. Clin Chem 2014; 60(4):600-9. PMC3972312

2013

Deng X, Song Y, Manson JE, Signorello LB, Zhang SM, Shrubsole MJ, Ness RM, Seidner DL, Dai Q. Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med 2013; 11:187. PMC3765911

Engelman CD, Meyers KJ, Iyengar SK, Liu Z, Karki CK, Igo RP Jr, Truitt B, Robinson J, Sarto GE, Wallace R, Blodi BA, Klein ML, Tinker L, LeBlanc ES, Jackson RD, Song Y, Manson JE, Mares JA, Millen AE. Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrations. J Nutr 2013; 143(1):17-26. PMC3521459

Hiraki LT, Qu C, Hutter CM, Baron JA, Berndt SI, Bézieau S, Brenner H, Caan BJ, Casey G, Chang-Claude J, Chanock SJ, Conti DV, Duggan D, Fuchs CS, Gallinger S, Giovannucci EL, Harrison TA, Hayes RB, Hazra A, Henderson B, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Küry S, Le Marchand L, Lemire M, Ma J, Manson JE, Nan H, Newcomb PA, Ng K, Potter JD, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Wactawski-Wende J, White E, Wu K, Zanke BW, Kraft P, Peters U, Chan AT. Genetic predictors of circulating 25-hydroxyvitamin D and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2013; 22(11):2037-46. PMC3818310

Song Y, Wang L, Pittas AG, Del Gobbo LC, Zhang C, Manson JE, Hu FB. Blood 25-hydroxy vitamin D levels and incident type 2 diabetes: a meta-analysis of prospective studies. Diabetes Care 2013; 36(5):1422-8. PMC3631862

Thadhani RI, Manson JE. Vitamin D: too soon to turn out the lights? Arterioscler Thromb Vasc Biol 2013; 33(11):2467-9.

Wang L, Ma J, Manson JE, Buring JE, Gaziano JM, Sesso HD. A prospective study of plasma vitamin D metabolites, vitamin D receptor gene polymorphisms, and risk of hypertension in men. Eur J Nutr 2013; 52(7):1771-9. PMC3609910

2012

Danik JS, Manson JE. Vitamin D and cardiovascular disease. Curr Treat Options Cardiovasc Med 2012; 14(4):414-24. PMC3449318

Manson JE, Bassuk SS, Lee IM, Cook NR, Albert MA, Gordon D, Zaharris E, MacFadyen JG, Danielson E, Lin J, Zhang SM, Buring JE. The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease. Contemp Clin Trials 2012; 33(1):159-71. PMC3253961

Rejnmark L, Avenell A, Masud T, Anderson F, Meyer HE, Sanders KM, Salovaara K, Cooper C, Smith HE, Jacobs ET, Torgerson D, Jackson RD, Manson JE, Brixen K, Mosekilde L, Robbins JA, Francis RM, Abrahamsen B. Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials. J Clin Endocrinol Metab 2012; 97(8):2670-81. PMC3410276

Rosen CJ, Adams JS, Bikle DD, Black DM, Demay MB, Manson JE, Murad MH, Kovacs CS. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev 2012; 33(3):456-92. PMC3365859

Sun Q, Pan A, Hu FB, Manson JE, Rexrode KM. 25-hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis. Stroke 2012; 43(6):1470-7. PMC3361562

Wang L, Song Y, Manson JE, Pilz S, März W, Michaëlsson K, Lundqvist A, Jassal SK, Barrett-Connor E, Zhang C, Eaton CB, May HT, Anderson JL, Sesso HD. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies. Circ Cardiovasc Qual Outcomes 2012; 5(6):819-29. PMC3510675

Wolpin BM, Ng K, Bao Y, Kraft P, Stampfer MJ, Michaud DS, Ma J, Buring JE, Sesso HD, Lee IM, Rifai N, Cochrane BB, Wactawski-Wende J, Chlebowski RT, Willett WC, Manson JE, Giovannucci EL, Fuchs CS. Plasma 25-hydroxyvitamin D and risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev 2012; 21(1):82-91. PMC3253914

2011

Bertone-Johnson ER, Powers SI, Spangler L, Brunner RL, Michael YL, Larson JC, Millen AE, Bueche MN, Salmoirago-Blotcher E, Liu S, Wassertheil-Smoller S, Ockene JK, Ockene I, Manson JE. Vitamin D intake from foods and supplements and depressive symptoms in a diverse population of older women. Am J Clin Nutr 2011; 94(4):1104-12. PMC3173027

Chacko SA, Song Y, Manson JE, Van Horn L, Eaton C, Martin LW, McTiernan A, Curb JD, Wylie-Rosett J, Phillips LS, Plodkowski RA, Liu S. Serum 25-hydroxyvitamin D concentrations in relation to cardiometabolic risk factors and metabolic syndrome in postmenopausal women. Am J Clin Nutr 2011; 94(1):209-17. PMC3127524

Kriegel MA, Manson JE, Costenbader KH. Does vitamin D affect risk of developing autoimmune disease?: a systematic review. Semin Arthritis Rheum 2011; 40(6):512-531.e8. PMC3098920

Manson JE, Mayne ST, Clinton SK. Vitamin D and prevention of cancer—ready for prime time? N Engl J Med 2011; 364(15):1385-7.

Melamed ML, Manson JE. Vitamin D and cardiovascular disease and cancer: not too much and not too little? The need for clinical trials. Womens Health (Lond) 2011; 7(4):419-24. PMC4378570

Michael YL, Smit E, Seguin R, Curb JD, Phillips LS, Manson JE. Serum 25-hydroxyvitamin D and physical performance in postmenopausal women. J Womens Health (Larchmt) 2011; 20(11):1603-8. PMC3216069

Robinson JG, Manson JE, Larson J, Liu S, Song Y, Howard BV, Phillips L, Shikany JM, Allison M, Curb JD, Johnson KC, Watts N. Lack of association between 25(OH)D levels and incident type 2 diabetes in older women. Diabetes Care 2011; 34(3):628-34. PMC3041195

Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 2011; 96(1):53-8. PMC3046611

Shapses SA, Manson JE. Vitamin D and prevention of cardiovascular disease and diabetes: why the evidence falls short. JAMA 2011; 305(24):2565-6. PMC4014631

Sun Q, Shi L, Rimm EB, Giovannucci EL, Hu FB, Manson JE, Rexrode KM. Vitamin D intake and risk of cardiovascular disease in US men and women. Am J Clin Nutr 2011; 94(2):534-42. PMC3142728

2010

Bassuk SS, Manson JE. Does vitamin D protect against cardiovascular disease? J Cardiovasc Transl Res 2009; 2(3):245-50.

Manson JE. Vitamin D and the heart: why we need large-scale clinical trials. Cleve Clin J Med 2010; 77(12):903-10.

Pittas AG, Sun Q, Manson JE, Dawson-Hughes B, Hu FB. Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in women. Diabetes Care 2010; 33(9):2021-3. PMC2928356

Rosen CJ, Manson JE. Frailty: a D-ficiency syndrome of aging? J Clin Endocrinol Metab 2010; 95(12):5210-2.

Wang L, Manson JE, Song Y, Sesso HD. Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Intern Med 2010; 152(5):315-23.

2009

Kaushik M, Mozaffarian D, Spiegelman D, Manson JE, Willett WC, Hu FB. Long-chain omega-3 fatty acids, fish intake, and the risk of type 2 diabetes mellitus. Am J Clin Nutr 2009; 90(3):613-20. PMC2728645